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MR-PRESSO detected outliers in the overall associations with CAD in FinnGen (shown in Additional file 1: Table S5), where we used corrected estimates from MR-PRESSO

A box was constructed to fully enclose the small molecule and protein by adjusting the Grid Box parameters, followed by running AutoGrid 4, setting the docking parameters and algorithms, running AutoDock4, and exporting the results file in PDBQT format

This recomposition is the GH effect at work: it selectively preserves lean mass while mobilizing fat

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