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Cysteine peptide trials (similar mechanism) showed improvement over 12 weeks at 250 mg/day

What is supported in animal models Increased lipolysis, increased fat oxidation, decreased lipogenesis, no apparent effect on plasma glucose or insulin sensitivity, and signal that intact beta-3 adrenergic receptor activity matters for the fat-loss effect

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Sci Rep 10(1):2259 Lora J, Alonso FJ, Segura JA, Lobo C, Mrquez J, Mats JM (2004) Antisense glutaminase inhibition decreases glutathione antioxidant capacity and increases apoptosis in Ehrlich ascitic tumour cells