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Minor redness is not a contraindication, but where there is itching or vesicle formation or excessive inflammatory response further treatment is not advised

Plasma, tumor and tissue pharmacokinetics of Docetaxel delivered via nanoparticles of different sizes and shapes in mice bearing SKOV-3 human ovarian carcinoma xenograft

The drug reaches its maximum concentration, known as Cmax, somewhere between 8 and 72 hours after injection