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Issues such as small sample sizes, lack of control groups, and short follow-up periods further weaken the validity of these studies

Delivery, Dosing, and Practical Considerations: What We Know (and Dont) Before exploring Epitalons cellular mechanisms, its important to ask a practical question: how is this peptide actually delivered, and what do we know about dosing

doi: 10.3389/fendo.2022.810242 Received 06 November 2021 Accepted 24 January 2022 Published 21 February 2022 Volume 13 - 2022 Edited by Davor Jezek, University of Zagreb, Croatia Reviewed by Gian Maria Busetto, University of Foggia, Italy

No differences were observed between the agent involved and the symptoms experienced, however tirzepatide and liraglutide exposures resulted in higher incidence of nausea (33.3% and 31.8%, respectively)