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While the VizAblate device is not currently available as a treatment option in the United States, the results of an international multi-center 12-month study were published in late 2014

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Since only the leak pathway varies with inflammation, this concept provides a solid foundation for the use of the above-described ratio measurements, in that the pore pathways transport the small molecules such as mannitol or 400 (Da) fluorescein isothiocyanate (FITC) 400 whereas larger molecules such as lactulose and FITC 4000 are transported by the variable leak pathway