Aged female NMRI mice (12-month-old) that received a diet with the ligustroside (50 mg/kg, 6.25 mg/kg body weight) for a period of 6 months showed an improvement in spatial working memory as compared to aged-control untreated mice
13.1 Carcinogenesis, Mutagenesis, Impairment of Fertility A 104-week carcinogenicity study was conducted in male and female CD-1 mice at doses of 0.03, 0.2, 1.0, and 3.0 mg/kg/day liraglutide administered by bolus subcutaneous injection yielding systemic exposures 0.2-, 2-, 10- and 45-times the human exposure, respectively, at the MRHD of 1.8 mg/day based on plasma AUC comparison
A companion eye-cream study in 41 women compared GHK-Cu cream to placebo and vitamin K and reported greater periorbital improvement
Cell Metab, 26(4), 611619