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The following section extends this integrative perspective to neuroendocrine and immunemetabolic peptide systems, where complexity has similarly constrained translation despite compelling biological rationale

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Groups of male mice (1213 weeks, 22.528.5 g, 56 mice/23 cages/group) were fasted for 4 h prior to IP injection of unfused WT albumin (0.9 mg/kg) or GLP-1 albumin fusions (1 mg/kg)