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After working with hundreds of people on GLP-1 medications, I've seen the pattern: those who succeed long-term aren't just taking their medication

Conditional deletion of the circadian clock gene Bmal1 (brain and muscle ARNT-like 1, also known as Arntl ) in glomerular podocytes caused disruption of the circadian rhythm in GFR and parallel alterations in the circadian patterns of plasma aldosterone levels and urinary excretion of creatinine, sodium, potassium, and water (11)

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