The brand describes it as "a more effective form of L-Arginine that improves circulation." AAKG is more commonly studied in the sports nutrition context for exercise performance than in blood pressure-specific research

Serious side effects (rare but important) Stop your medication and contact your healthcare provider immediately if you experience: Severe, persistent abdominal pain that radiates to your back (possible pancreatitis, occurring in less than 1% of patients) Signs of gallbladder problems including intense upper-right abdominal pain, fever, and jaundice (approximately 2 to 3% incidence) Symptoms of allergic reaction including facial swelling, difficulty breathing, or widespread rash (less than 1%) Signs of kidney problems including changes in urine output, swelling in legs or ankles, or unusual fatigue Any thoughts of self-harm (reported in post-marketing surveillance) The B12 advantage for side effect management One theoretical advantage of the compounded B12 formulation is the potential to reduce fatigue and maintain neurological function during aggressive caloric restriction

Reportedly, VEGF signaling increases VEGFR2 expression and phosphorylation, and stimulates proliferation in VEGF-stimulated C2C12 cells (Supplementary Figure S2), and this might potentially reduce the effects of lenvatinib and L-carnitine in C2C12 cells
In general, low-fiber diets tend to bring about constipation since a lack of bulk-forming fiber doesnt assist in the movement of fecal matter through the colon