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Regulatory approval : Mazdutide is approved in China for T2D

Tirzepatide# Tirzepatide is a 39-amino acid synthetic peptide that activates both the GIP receptor (GIPR) and the GLP-1 receptor

This matters because it shows how researchers expand the endpoint set depending on population and protocol: weight endpoints remain central, while glycaemic endpoints are included when the population and study design require them

risk of edema, fractures, bladder cancer Non-Insulin Injectable Agents (assign Z79.85): GLP-1 receptor agonists (semaglutide, liraglutide, dulaglutide, tirzepatide [dual GIP/GLP-1]): Cardiovascular and renal protective