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Despite reduced appetite, patients should aim to consume regular, balanced meals containing: Adequate protein (lean meats, fish, eggs, legumes, dairy) to support muscle mass and energy metabolism Complex carbohydrates (whole grains, vegetables, fruits) for sustained energy release Healthy fats (nuts, seeds, olive oil, avocado) for satiety and nutrient absorption Micronutrients from a varied diet, particularly foods containing B vitamins, iron, and vitamin D, which are essential for energy production Small, frequent meals may be better tolerated than large portions, helping to manage nausea whilst ensuring sufficient caloric intake

doi: 10.1152/ajpendo.90644.2008 26

This effect is not observed in other GLP-1RAs and is currently being studied by the drug manufacturers in the FOCUS trial (NCT03811561)