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We also chose LIR, a longer-acting GLP-1 agonist, to reduce fluctuations in plasma levels and observe its effects over an extended study period (6 h), which should more closely mimic the human condition of drug exposure

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Neth J Med 66: 354357, 2008 [PubMed] [Google Scholar] 23.Green TJ, Bijlsma JJ, Sweet DD: Profound metabolic acidosis from pyroglutamic acidemia: An underappreciated cause of high anion gap metabolic acidosis