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Additionally, some patients report that certain injection sites may feel more sensitive at different times

The standard dosing schedule starts with 0.25 mg weekly for the first four weeks, increases to 0.5 mg weekly from weeks five through eight, and then may escalate to 1 mg or 2 mg weekly depending on tolerance and response

Bromodomain and Extra-Terminal Domain Bromodomain Inhibition Prevents Synovial Inflammation via Blocking Ib Kinase-Dependent NF-b Activation in Rheumatoid Fibroblast-Like Synoviocytes

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