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Knockdown of the Nrf2 gene reversed the protective effects of oysterin, resulting in increased expression of IL-1, IL-17A, and ROS, and decreased expression of HO-1 and SOD

Key aspects of the PESTO trial design include: While PESTO is designed to provide level 1 evidence on the safety and efficacy of perispinal etanercept in chronic stroke patients, the design has been criticized by some experts

ZJJ, KB, HYJ, and YYB analyzed the data and wrote the manuscript