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What that means isnt always straightforward: In the Swiss study mentioned above, nearly three-quarters of primary-care docs surveyed reported using a multi-step approach (and not always the same one) when testing for B12 deficiencya practice that Miller says improves the odds of an accurate diagnosis since serum B12 levels alone dont always accurately identify a deficiency
However, long-term activation of an opioid receptor with either chronic use or abuse of opioids leads to highly undesirable and clinically significant side effects
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