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There is strong evidence that GLP-1 medications can: Improve HbA1c and blood glucose control Support appetite regulation Improve cardiovascular risk markers in some populations Support improvements in cholesterol and triglycerides Lower blood pressure (modestly) Reduce risk of major cardiovascular events in higher-risk individuals For many people, these changes occur independently of weight reduction and are linked to improved metabolic functioning

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A separate meta-analysis that pooled results of trials in older adults with mild cognitive impairment found B-vitamin supplementation (6 to 24 months, depending on the trial) had no benefits on various cognitive parameters, including executive function, information processing speed, and episodic memory (90)

For this reason, we will continue to report our results for these questions weighted by the number of covered workers in responding firms