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Separately, over 200 subjects on semaglutide lost an average of 15.2 percent of their body weight after 104 weeks, per a study published in the journal Nature Medicine in 2022
In a novel object recognition (NOR) paradigm, Bbs5 / mice spent less time exploring the novel object than did WT littermates, which was indicative of memory retention deficits (Figure 1G)
Semaglutide side effects, such as nausea, vomiting, and bloating, are among the most frequently reported, and tirzepatide side effects follow a similar pattern, though individual experiences may vary