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With regards to the claims made that the treatment is virtually painless, we struggle to ever support that anything injected into the body is pain free, yes discomfort can be minimised when performing aesthetic procedures but we struggle to see how a procedure that takes needle to skin and has the mechanism of eliminating tissue from the body can be virtually devoid of pain

However, if you find the side effects too challenging or if the morning injections arent manageable with your schedule, transitioning to evening injections could be beneficial

The procedure is quick, taking only a few seconds, and most patients report minimal discomfortsimilar to other intramuscular injections such as vaccines

A hierarchical testing strategy was used in PIONEER 5 and 6