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CYP2E1 and ALDH enzymatic activity CYP2E1 activity was assessed by measuring the rate of oxidation of p -nitrophenol (PNP) to p -nitrocatechol as described 54

10.3349/ymj.2017.58.3.570 67 LeeW.-S.KimH

TGR inhibitors identified to date are irreversible and/or covalent inhibitors with unacceptable off-target effects

The implications of our research suggest that rutin-loaded nanoparticles offer a promising novel therapeutic approach for IBD, presenting a safer and more tolerable alternative to conventional treatments