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References Risbud MV, Schaer TP, Shapiro IM: Toward an understanding of the role of notochordal cells in the adult intervertebral disc: from discord to accord

If that trial confirms the Lancet findings at scale, a regulatory submission would follow, but approval before 2029 is unlikely

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Finally, nanoparticles are also being used to carry therapeutic agents across the BBB (Belgamwar et al